First external validation of our mdbrain aneurysm module published in AJNR

New study from the University of Bonn shows 100% sensitivity for therapeutically relevant saccular aneurysms larger than 5mm.

According to current studies, about 15% of intracranial aneurysms are initially overlooked. Which was also confirmed by the current study of Nils Lehnen (University of Bonn).

In the published study, mdbrain reliably detected 100% of saccular aneurysms with a therapeutically relevant size of 5mm or larger, without detecting too many false positive cases.

In the following example, a large thrombosed aneurysm was reliably detected by the radiologist (arrow), but the smaller aneurysm on the opposite side was overlooked. mdbrain reliably detected both and color coded as well as framed the aneurysms for better visualization.

Source: Automated Detection of Cerebral Aneurysms on TOF-MRA Using a Deep Learning Approach: An External Validation Study, N.C. Lehnen et al., American Journal of Neuroradiology November 2022, DOI: https://doi.org/10.3174/ajnr.A7695.

In the total test population 54 aneurysms of very heterogeneous size and location were identified based on 191 patients and the overall accuracy was 82.6% (specificity 87.2%; sensitivity 70.4%).

Thus, the system can make an important contribution in everyday clinical routine regarding quality assurance and screening, but also follow-up of previously untreated aneurysms.

If you would like to learn more about the validation results of our aneurysm module, you can read the full publication in the American Journal of Neuroradiology (AJNR) here.

The award-winning method is available in the commercial product mdbrain 4.7 - make your appointment here for a personal product demo.

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10965 Berlin, Germany

P +49 30 286 490 67
F +49 30 286 490 66

© 2022 mediaire GmbH