{
    "id": 21465,
    "date": "2023-07-12T16:51:00",
    "date_gmt": "2023-07-12T14:51:00",
    "guid": {
        "rendered": "https:\/\/mediaire.ai\/?p=21465"
    },
    "modified": "2025-09-03T09:06:32",
    "modified_gmt": "2025-09-03T07:06:32",
    "slug": "evaluation-of-cerebral-volume-changes-in-patients-with-tremor-treated-by-mrgfus-thalamotomy",
    "status": "publish",
    "type": "post",
    "link": "https:\/\/mediaire.ai\/de\/evaluation-of-cerebral-volume-changes-in-patients-with-tremor-treated-by-mrgfus-thalamotomy\/",
    "title": {
        "rendered": "Evaluation of Cerebral Volume Changes in Patients with Tremor Treated by MRgFUS Thalamotomy"
    },
    "content": {
        "rendered": "<div data-elementor-type=\"wp-post\" data-elementor-id=\"21465\" class=\"elementor elementor-21465\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4f80ddb3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4f80ddb3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e960e4f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e960e4f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f5f4466\" data-id=\"f5f4466\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d3e8339 elementor-widget elementor-widget-heading\" data-id=\"d3e8339\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Published in<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-328c2c2 elementor-widget elementor-widget-text-editor\" data-id=\"328c2c2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><\/p>\n<p><em>Life<\/em>\u00a0(2023), 13(1):16<\/p>\n<p><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41587d4 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"41587d4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d941db5 elementor-widget elementor-widget-heading\" data-id=\"d941db5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Authors<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-03e67b3 elementor-widget elementor-widget-text-editor\" data-id=\"03e67b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><\/p>\n<p>Bruno, F., Tommasino, E., Catalucci, A., Pastorelli, C., Borea, F., Caldarelli, G., Bellini, M., Badini, P., Mancini, S., Santobuono, C., et al.<\/p>\n<p><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a759acf elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"a759acf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9dfe6e7 elementor-widget elementor-widget-heading\" data-id=\"9dfe6e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Abstract<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9fc7e74 elementor-widget elementor-widget-text-editor\" data-id=\"9fc7e74\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div id=\"sec-1\" class=\"subsection\">\n<p id=\"p-1\">The purpose of the study is to quantify volumetric variations of cortical and subcortical brain structures after Vim ablation using MRgFUS, and correlate them with the patients\u2019 clinical features and treatment outcomes. For this pilot retrospective study we enrolled 31 patients with a mean age of 70.86 years who were eligible for unilateral Vim thalamotomy. Clinical evaluation included tremor severity assessment using the FTM scale and cognitive assessment using the MoCA score. MRI data were acquired with a 3T scanner, using a dedicated 32-channel coil and acquiring a volumetric sequence of T1 3D IR FSPGR (BRAVO), before treatment and one year after MRgFUS thalamotomy. Image processing and volume data extraction were conducted with dedicated software. A volumetric analysis showed a significant reduction (<span class=\"html-italic\">p<\/span>\u00a0&lt; 0.05) of the left thalamus 1 year after the treatment in patients with ET. Other significant results were found on the same side in the other nuclei of the basal ganglia and in the cerebellar cortex. In confronting the two groups (ET, PD), no significant differences were found in terms of age, FTM, MoCA scores, or brain volumes. Similarly, no significant correlations were found between the FTM and MoCA scores and the brain volumes before the treatment.<\/p>\n<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a638a74 elementor-mobile-align-left elementor-widget elementor-widget-button\" data-id=\"a638a74\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;none&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.mdpi.com\/2075-1729\/13\/1\/16\" target=\"_blank\" download=\"poster_effectofmriacquisition.pdf\" rel=\"nofollow noopener\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read Full Publication<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>",
        "protected": false
    },
    "excerpt": {
        "rendered": "<p>The purpose of the study is to quantify volumetric variations of cortical and subcortical brain structures after Vim ablation using MRgFUS, and correlate them with the patients\u2019 clinical features and treatment outcomes. For this pilot retrospective study we enrolled 31 patients with a mean age of 70.86 years who were eligible for unilateral Vim thalamotomy.<\/p>",
        "protected": false
    },
    "author": 1,
    "featured_media": 0,
    "comment_status": "open",
    "ping_status": "open",
    "sticky": false,
    "template": "",
    "format": "standard",
    "meta": {
        "_acf_changed": false,
        "footnotes": ""
    },
    "categories": [
        14
    ],
    "tags": [],
    "class_list": [
        "post-21465",
        "post",
        "type-post",
        "status-publish",
        "format-standard",
        "hentry",
        "category-publications"
    ],
    "acf": [],
    "_links": {
        "self": [
            {
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/posts\/21465",
                "targetHints": {
                    "allow": [
                        "GET"
                    ]
                }
            }
        ],
        "collection": [
            {
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/posts"
            }
        ],
        "about": [
            {
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/types\/post"
            }
        ],
        "author": [
            {
                "embeddable": true,
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/users\/1"
            }
        ],
        "replies": [
            {
                "embeddable": true,
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/comments?post=21465"
            }
        ],
        "version-history": [
            {
                "count": 6,
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/posts\/21465\/revisions"
            }
        ],
        "predecessor-version": [
            {
                "id": 21629,
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/posts\/21465\/revisions\/21629"
            }
        ],
        "wp:attachment": [
            {
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/media?parent=21465"
            }
        ],
        "wp:term": [
            {
                "taxonomy": "category",
                "embeddable": true,
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/categories?post=21465"
            },
            {
                "taxonomy": "post_tag",
                "embeddable": true,
                "href": "https:\/\/mediaire.ai\/de\/wp-json\/wp\/v2\/tags?post=21465"
            }
        ],
        "curies": [
            {
                "name": "wp",
                "href": "https:\/\/api.w.org\/{rel}",
                "templated": true
            }
        ]
    }
}